Comparing Almadelic, Better U, and Mindbloom: Which is the Best Choice for Colorado Residents Seeking Alternative Mental Health Treatments?

Updated: 9/17/26

With mental health at the forefront of health conversations, many people are exploring alternative treatments for depression, anxiety, and PTSD. Almadelic, Better U, and Mindbloom all offer at-home ketamine-assisted therapy to Colorado residents, and all three are available without setting foot in a clinic. They differ in how treatment is delivered, how much support comes with it, what it costs, and whether insurance plays any role. Here is how they compare.

Quick answer: All three providers serve Colorado with at-home ketamine therapy. Better U is the lowest-cost option, with packages from $500. Mindbloom offers the widest reach and the only at-home injectable option. Almadelic is the only one of the three that also offers licensed online therapy and works with insurance, with many members qualifying for $0 copays on therapy.

How Do the Three Providers Compare at a Glance?

What Does Each Platform Offer?

Almadelic

Almadelic offers at-home ketamine therapy for depression, anxiety, PTSD, and other mental health challenges. Licensed clinicians conduct a thorough evaluation before treatment begins, and experienced guides support every session from preparation through integration. Services include:

Initial Consultation: A thorough evaluation with licensed clinicians to design a personalized treatment plan. Customized Treatment Plans: At-home ketamine sessions, supported by medical supervision. Ongoing Support: Access to resources such as coaching, follow-ups, and wellness guidance to help patients integrate the therapy's effects into their daily lives.

Almadelic operates in Colorado, Ohio, and Florida, and Colorado residents can find state-specific details on the Colorado at-home ketamine therapy page.

Two things have changed since this comparison was first published. Almadelic now also offers online therapy with licensed therapists in all three states, so ketamine treatment and ongoing talk therapy can live under one roof. Almadelic also works with most major insurance providers for online therapy, and many members qualify for $0 copays. Psilocybin-assisted therapy is on the way, with Colorado first.

Better U

Better U specializes in at-home ketamine therapy for conditions including depression, anxiety, PTSD, and chronic stress, combining telehealth consultations with ketamine sessions patients complete at home. Their program includes:

Telehealth Consultations: Virtual consultations to assess patient needs and recommend ketamine therapy if appropriate. Package-Based Plans: An Introduction package priced at $500 for 5 ketamine sessions and 1 integration coaching session, and a Transformation package at $792 for 9 sessions and 2 coaching sessions. Professional Guidance: Virtual check-ins and integration coaching alongside the sessions themselves.

Better U operates in roughly 30 states, Colorado included, offers financing, and publishes discounted pricing for veterans, medical workers, teachers, and first responders.

Mindbloom

Mindbloom focuses on protocol-driven at-home ketamine therapy backed by published research, and it has expanded considerably since 2024. Their model includes:

Medical Consultation: An initial telemedicine consultation to determine whether the patient qualifies for ketamine therapy. Two Administration Routes: Sublingual tablets or subcutaneous injectables, an option no other at-home provider currently offers. Guide Coaching and Integration: One-on-one coaching plus group integration sessions, supported by an app with preparation and journaling content.

Mindbloom operates in 38 or more states, including Colorado, with programs of 6, 12, or 18 sessions starting around $1,290 for six. It does not bill insurance directly, though programs are HSA and FSA eligible, and the company has published peer-reviewed outcomes research on its own protocol.

Which Provider Personalizes Treatment the Most?

Almadelic: Offers highly personalized treatment plans, designed by licensed clinicians based on each patient's unique mental health needs. Almadelic provides a "Welcome Package" for new clients and a "Renewal Package" for ongoing care, ensuring that treatment evolves with patient progress. Patients who also want talk therapy can be matched with a licensed therapist through the same platform. Better U: Offers two fixed packages, 5 sessions or 9, with integration coaching attached to each. Simple and predictable, but the structure does the deciding rather than a custom plan. Mindbloom: Personalizes primarily through route and program length, letting patients choose tablets or injectables across 6, 12, or 18 sessions.

Winner for Personalization: Almadelic, for its structured approach to ongoing care and the ability to pair ketamine treatment with licensed therapy for Colorado residents who want both.

How Accessible and Convenient Is Each Option?

Almadelic: Exclusively provides at-home therapy, with licensed professionals guiding each session remotely, a major convenience for those looking to avoid travel. Available in Colorado, Ohio, and Florida. Better U: Fully remote, available in about 30 states, with financing options that lower the barrier to starting. Mindbloom: Also fully remote and available in 38 or more states. The injectable option requires comfort with a small self-administered injection, which some patients prefer and others do not.

Winner for Accessibility: For Colorado residents specifically, all three are equally available, so this comes down to what kind of at-home experience you want rather than whether you can get care at all.

What Ongoing Support Does Each Provider Include?

Almadelic: Offers extensive support through follow-ups, coaching, and additional wellness resources, helping patients fully integrate the therapy's effects into their daily lives, with licensed therapists available for longer-term work. Better U: Includes 1 integration coaching session with the 5-session package and 2 with the 9-session package, plus virtual check-ins. Mindbloom: Provides one-on-one guide coaching and group integration sessions, along with app-based preparation and journaling content.

Winner for Ongoing Support: Almadelic, because integration coaching and ongoing therapy are part of the same platform rather than a fixed number of coaching sessions attached to a package.

What Does Each Provider Cost?

Almadelic: Provides clear treatment packages for new and returning clients, with a focus on long-term well-being, though pricing details are typically disclosed during consultation. Almadelic also accepts most major insurance for online therapy, and many members qualify for $0 copays, which neither competitor offers. You can check your coverage before booking. Better U: $500 for 5 sessions or $792 for 9, with financing available, making it the lowest sticker price of the three. Mindbloom: Around $1,290 for a six-session program, billed monthly, with lower per-session rates on the 12 and 18-session programs. Cash pay, HSA and FSA eligible.

Winner for Cost: Better U on price alone. For patients who want ketamine treatment and ongoing therapy, Almadelic's insurance acceptance changes the total picture, since therapy is the recurring cost over time and is the piece insurance is most likely to cover.

Final Verdict: Which Platform Is Best for Colorado Residents?

Each platform has its strengths. Better U is the most affordable entry point, and Mindbloom offers the broadest reach and the only at-home injectable option. For Colorado residents, Almadelic stands out for three reasons:

At-Home Comfort and Convenience: Almadelic is built around at-home therapy, allowing patients to experience treatment in a familiar, comfortable environment. Personalized and Ongoing Care: Almadelic's treatment model emphasizes continuous support, with packages that evolve as patients progress, which suits people looking for a long-term solution rather than a fixed package. Ketamine and Therapy Together: Almadelic is the only one of the three that also offers licensed online therapy and works with insurance, so the medicine and the therapeutic work happen in the same place.

For Colorado residents interested in alternative, comprehensive mental health treatment, Almadelic offers a level of customization, at-home accessibility, and ongoing support that makes it a top choice. Schedule a free consultation with Almadelic to talk through your options.

Frequently Asked Questions

Is at-home ketamine therapy available in Colorado?

Yes. Almadelic, Better U, and Mindbloom all serve Colorado residents with at-home ketamine therapy, delivered through telehealth with medication shipped to your home.

How much does at-home ketamine therapy cost in Colorado?

Better U packages run $500 for 5 sessions and $792 for 9. Mindbloom programs start around $1,290 for six sessions. Almadelic discloses pricing during consultation.

Does insurance cover at-home ketamine therapy?

At-home ketamine programs are generally cash pay. Almadelic accepts most major insurance for online therapy, and many members qualify for $0 copays, so patients combining therapy with ketamine treatment may be able to use their benefits for the therapy portion of their care.

Which provider is best if I want therapy alongside ketamine treatment?

Almadelic, since licensed online therapists are part of the same platform in Colorado, Ohio, and Florida.