
How to Prepare for Your At-Home Ketamine Therapy Session
Preparation plays a direct role in the quality of your ketamine therapy experience. The right environment, mindset, and physical readiness can help you feel safe, reduce side effects, and get more from each session. This guide covers everything you need to know before, during, and after your at-home ketamine therapy session.
Before Your Ketamine Session

Diet and Fasting
Eating a clean, healthy diet in the days leading up to your session can support your overall well-being and help your body respond to treatment more effectively. Avoid processed foods when possible.
On the day of your session, fast for 4 to 6 hours before your scheduled time. This minimizes the risk of nausea and vomiting during treatment. Clear liquids like water, clear juice, or herbal tea are fine up to 2 hours before your session. Drinking warm water with lemon or hot tea before your session can also help increase the absorbability of your medication.

Setting Up Your Space
Your surroundings directly shape your ketamine therapy experience. A calm, controlled environment reduces distractions and external stress so you can fully engage with the therapeutic process.
Choose a quiet, private location.
Pick a room where you feel relaxed and won't be disturbed. A bedroom, living room, or meditation space can all work well. Make sure the space is free from loud noises, bright lights, and electronic interruptions. For more detailed guidance, review our complete guide to creating your space.
Mental and Emotional Preparation
Set your intentions.
Take time before your session to reflect on why you chose this work. What are you hoping to explore, release, or understand? Journaling your thoughts or talking them through with a trusted person or your therapist can bring clarity. Research has found that setting an intention before a psychedelic experience helps focus the mind and prime the psyche for the work ahead.Some examples of intentions:

Confirm Your Support Person
Make sure your adult support person (chaperone) is confirmed and available before you begin your session. Depending on your comfort level, this person may sit with you during the session or remain just outside your space, within earshot in case you need them.
If it's your first session, having someone present is especially important. Even if you prefer to be alone during the experience itself, make sure someone checks in on you afterward. For more detail on the chaperone's role, visit our role of chaperone resource page.

What to Wear
Comfort matters. Wear loose-fitting clothing made of natural fabrics like cotton or linen. You'll want to be able to fully relax without any physical distractions. Consider wearing socks and comfortable footwear as well, since body temperature can fluctuate during a session.

Monitor Your Vitals
If you have hypertension or elevated blood pressure, use a blood pressure cuff before and during your session. Your readings should stay below the following thresholds:
- Systolic (upper number): below 155
- Diastolic (lower number): below 95

During Your Session: How to Administer Your Ketamine Troche
Ketamine troches are designed for sublingual (under the tongue) use. Holding the troche under the tongue significantly increases its effectiveness compared to swallowing.

Step by step:
- 1.
Set your intention in a few words before you begin. It can help to write it down in your journal and refer back to it during post-session integration.
- 2.
Place the troche under your tongue.
- 3.
Hold it there until it is entirely dissolved.
- 4.
Continue holding the dissolved medication and any saliva that builds up for at least 15 minutes.
- 5.
Spit it out after 15 minutes. While it is safe to swallow, we do not recommend it. Swallowing may upset your stomach and can increase the duration of side effects like dizziness or nausea.
Tips for better absorption:
Drink warm water with lemon or hot tea before your session to help increase absorbability.
Do not eat solid foods and drink only clear liquids for at least 4 hours before using the medication.
Have your trusted support person present when you administer the medication at home.
After Your Session: Integration and Recovery
The hours and days after a ketamine session are just as important as the session itself. This is when insights settle and new patterns begin to take hold.
Give yourself time to recover. As the effects wear off, you'll gradually return to your normal state. This may take 30 minutes to an hour. Rest during this time and avoid activities that require alertness or coordination.
Reflect and journal. Write down any thoughts, emotions, images, or insights that came up during the session. These details can fade quickly, so capturing them soon after is valuable. You can share your notes with your care team during follow-up.
Engage in light activity. Gentle movement like walking or stretching can help you feel grounded as you come back to your normal state.
Avoid overstimulation. Skip social media, intense conversations, and alcohol in the hours after your session. Give your mind space to process the experience without external noise.
Stay hydrated and nourished. Drink plenty of water after your session. When you're ready to eat, keep it light. Soups, herbal teas, nuts, and fruit are gentle on the stomach and help stabilize your energy. Avoid heavy, greasy foods or excessive caffeine.
Many people find that the insights from a ketamine session become clearer over the following days. Taking time for reflection and self-care supports the integration process and helps turn the experience into lasting benefit.

Questions About Preparation?
If you have any questions about how to prepare for your session, reach out to our care team for guidance based on your specific needs and situation. You can also visit our complete FAQ for answers to common questions about at-home ketamine therapy.